Publications

 

Khodosevich K, Dragicevic K, Howes O (2023) Drug targeting in psychiatric disorders – how to overcome the loss in translation? Nat Rev Drug Discovery, s41573-023-00847-7 

Lemcke R, Egebjerg C, Berendtsen NT, Egerod KL, Thomsen AR, Pers TH, Christensen JP, Kornum BR (2023) Molecular consequences of peripheral Influenza A infection on cell populations in the murine hypothalamus. Elife, 12:RP87515

Palani NP, Horvath C, Timshel PN, Folkertsma P, Grønning AGB, Henriksen TI, Peijs L, Jensen VH, Sun W, Jespersen NZ, Wolfrum C, Pers TH, Nielsen S, Scheele C (2023) Adipogenic and SWAT cells separate from a common progenitor in human brown and white adipose depots. Nat Metab, 5(6):996-1013.

Lee J, Møller AF, Chae S, Bussek A, Park TJ, Kim Y, Lee HS, Pers TH, Kwon T, Sedzinski J, Natarajan KN (2023) A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development. Sci Adv, 9(14):eadd5745.

O'Rourke C, Salati M, Rae C, Carpino G, Leslie H, Pea A, Prete M, Bonetti L, Amato F, Montal R, Upstill-Goddard R, Nixon C, Sanchon-Sanchez P, Kunderfranco P, Sia D, Gaudio E, Overi D, Cascinu S, Hogdall D, Pugh S, Domingo E, Primrose J, Bridgewater J, Spallanzani A, Gelsomino F, Llovet J, Calvisi D, Boulter L, Caputo F, Lleo A, Jamieson N, Luppi G, Dominici M, Andersen J, Braconi C (2023) Molecular portraits of patients with intrahepatic cholangiocarcinoma who diverge as rapid progressors or long survivors on chemotherapy. Gut, doi: 10.1136/gutjnl-2023-330748

Ford S, Buus T, Nastasi C, Geisler C, Bonefeld C, Ødum  N, Woetmann A (2023) In vitro differentiated human CD4+ T cells produce hepatocyte growth factor. Front Immunol, 14:1210836

Karin F, Ferretti E (2023) Derivation of Human Extraembryonic Mesoderm-like Cells from Primitive Endoderm. Int J Mol Sci, 24(14):11366

Schmøkel S, Nordentoft  I, Lindskrog S, Lamy P, Knudsen M, Jensen J, Dyrskjøt L (2023) Improved protocol for single-nucleus RNA-sequencing of frozen human bladder tumor biopsies. Nucleus, 14(1):2186686

Pærregaard S, Wulff L, Schussek S, Niss K, Mörbe U, Jendholm J, Wendland K, Andrusaite A, Brulois K, Nibbs R, Sitnik K, Mowat A, Butcher E, Brunak S, Agace W (2023) The small and large intestine contain related mesenchymal subsets that derive from embryonic Gli1+ precursors. Nat Commun, 14(1):2307

Peiffer L, Gambichler T, Buus T, Horny K, Gravemeyer J, Furtmann F, Spassova I, Kubat L, Susok L, Stranzenbach R, Srinivas N, Ødum N, Becker J (2023) Phenotypic plasticity of malignant T cells in blood and skin of a Sézary syndrome patient revealed by single cell transcriptomics. Front Oncol, 13:1090592

Gluud M, Pallesen E, Buus T, Gjerdrum L, Lindahl L, Kamstrup M, Bzorek M, Danielsen R, Bech R, Monteiro E, Blümel E, Willerslev-Olsen A, Lykkebo-Valløe A, Vadivel C, Krejsgaard T, Bonefeld C, Geisler C, Becker J, Koralov S, Iversen L, Litman T, Woetmann A, Ødum N (2023) Malignant T cells induce skin barrier defects through cytokine-mediated JAK/STAT signaling in cutaneous T-cell lymphoma. Blood, 141 (2): 180–193

 

 

Batiuk M, Tyler T, Dragicevic K, Mei S, Rydbirk R, Petukhov V, Deviatiiarov R, Sedmak D, Frank E, Feher V, Habek N, Hu Q, Igolkina A, Roszik L, Pfisterer U, Garcia-Gonzalez D, Petanjek Z, Adorjan I, Kharchenko P, Khodosevich K (2022) Upper cortical layer–driven network impairment in schizophrenia. Sci Adv 8, doi:10.1126/SCIADV.ABN8367

Petukhov V, Igolkina A, Rydbirk R, Mei S, Christoffersen L, Khodosevich K, Kharchenko P (2022). Case-control analysis of single-cell RNA-seq studies. bioRxiv 2022.03.15.484475.

Kim D, Kim J, Yu Y, Kim Y, Baek S, Won KJ (2022) Systemic approaches using single cell transcriptome reveal that C/EBPγ regulates autophagy under amino acid starved condition. Nucl Acid Res, 13:7298–7309

Malwade S, Gasthaus J, Bellardita C, Andelic M, Moric B, Korshunova I, Kiehn O, Vasistha NA, Khodosevich K (2022) Identification of vulnerable interneuron subtypes in 15q13.3 microdeletion syndrome using single-cell transcriptomics. Biol Psychiatry, 91(8): 727-739

Pedersen  C,  Dam  S, Barnkob M, Leipold  M,  Purroy N, Rassenti L, Kipps  T, Nguyen J, Lederer  J, Gohil  S, Wu C, Olsen L (2022) cyCombine allows for robust integration of single-cell cytometry datasets within and across technologies. Nat Commun, 13(1):1698

Bergmann T, Liu Y, Skov J, Mogus L, Lee J, Pfisterer U, Hand L, Asenjo-Martinez A, Vargas I, Seemann S, Tsz J, Lee H, Patikas N, Kornum B, Denham M, Hyttel P, Witter M, Gorodkin J, Pers T, Hemberg M, Khodosevich K, Hall V (2022) Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming. Front Cell Dev Biol, 10: 1–23

Kohler K, Goldhammer N, Demharter S, Pfisterer U, Khodosevich K, Rønnov-Jessen L, Petersen O, Villadsen R, Kim J (2022) Ductal keratin 15+ luminal progenitors in normal breast exhibit a basal-like breast cancer transcriptomic signature. npj Breast Cancer, 8: 1–12

Pazarlar B, Aripaka S, Petukhov V, Pinborg L, Khodosevich K, Mikkelsen J (2022) Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE). Mol Brain, 15: 45

 

 

     

     

     

     

     

     

    Buus T, Willerslev-Olsen A, Fredholm S, Blümel E, Nastasi C, Gluud M, Hu T, Lindahl L, Iversen L, Fogh H, Gniadecki R, Litvinov I, Persson J, Bonefeld C, Geisler C, Christensen J, Krejsgaard T, Litman T, Woetmann A, Ødum N (2018) Single-cell heterogeneity in Sézary syndrome. Blood Adv, 2 (16): 2115–2126